焦文标

姓名

焦文标

性别

职称

研究员

学位

博士

电话


邮箱

jiao@mail.hzau.edu.cn

工作单位

华中农业大学信息学院

研究方向

计算基因组学,生物信息学,进化基因组学

教育经历

2006.9-2010.6   华中农业大学,生物学基地班,学士

2010.9-2013.6   华中农业大学,生物化学与分子生物学,硕士

2014.1-2018.1   德国科隆大学,生物信息学,博士

2014.1-2017.6   德国,马克斯普朗克植物育种研究所博士

主要职历

2017.7-2020.12 德国马克斯普朗克植物育种研究所,博士后

2021.1-2021.3   德国慕尼黑大学 ,博士后

2021.4-至今       华中农业大学信息学院,生物信息系

园艺植物生物学教育部重点实验室,研究员,博导

科研成果

欢迎有生物信息学、生物学、计算机科学、数学等背景的本科生, 硕士/博士研究生,博后加入我们课题组。(办公室 逸夫楼C508)


本课题组依托华中农业大学信息学院和园艺植物生物学教育部重点实验室,主要以柑橘类、油菜、马铃薯等园艺作物为研究对象,具体研究内容将主要围绕基因组突变、重组、遗传多态性、进化等基本生物学问题展开,结合现有的高通量组学技术(如三代测序技术、单细胞组学技术等)并在此基础上开发适用于特定研究的基因组学技术,并开发相应的生物信息学算法,以解决基因组组装、结构变异识别、基因组进化等计算基因组学领域的关键问题,为园艺作物的遗传改良和品质创新提供指导。


一作或共同一作文章

1. Jiao WB, Patel V, Klasen J, Liu F, Pecinkova P, Ferrand M: The   Evolutionary Dynamics of Genetic Incompatibilities Introduced by Duplicated Genes in Arabidopsis   thaliana, Molecular Biology and Evolution, 2020, msaa306 https://doi.org/10.1093/molbev/msaa306

2. Jiao WB,   Schneeberger K: Chromosome-level assemblies of multiple Arabidopsis genomes   reveal hotspots of rearrangements with altered evolutionary dynamics. Nat   Commun 2020, 11:989.

3. Jiao WB, Schneeberger K: The impact of third generation genomic   technologies on plant genome assembly. Curr Opin Plant Biol 2017, 36:64-70.

4. Jiao WB, Garcia Accinelli G, Hartwig B, Kiefer C, Baker D, Severing E,   Willing E-M, Piednoel M, Woetzel S, Madrid-Herrero E, et al.: Improving and   correcting the contiguity of long-read genome assemblies of three plant   species using optical mapping and chromosome conformation capture data. Genome   Res 2017, 27:778–786.

5. Jiao WB, Huang D, Xing F, Hu Y, Deng XX, Xu Q, Chen LL: Genome-wide   characterization and expression analysis of genetic variants in sweet orange.   Plant J 2013, 75:954–964.


合作参与文章

1. Campoy, J.A., Sun, H.,   Goel, M. Jiao WB, et al. Gamete binning: chromosome-level and   haplotype- resolved genome assembly   enabled by high-throughput single-cell sequencing of gamete genomes. Genome   Biol 21, 306 (2020).

2. Goel M, Sun H, Jiao WB,   Schneeberger K: SyRI: finding genomic rearrangements and local sequence   differences from whole-genome assemblies. Genome Biol 2019, 20:277.

3. Dittberner H, Becker C, Jiao   WB, Schneeberger K, Hölzel N, Tellier A, Meaux J: Strengths and potential   pitfalls of hay transfer for ecological restoration revealed by RAD‐seq   analysis in floodplain Arabis species. Mol Ecol 2019, 28:3887–3901.

4. Kiefer C, Willing E-M, Jiao   WB, Sun H, Piednoël M, Hümann U, Hartwig B, Koch MA, Schneeberger K:   Interspecies association mapping links reduced CG to TG substitution rates to   the loss of gene-body methylation. Nat Plants 2019, 5:846–855.

5. Zapata L, Ding J, Willing E,   Hartwig B, Bezdan D, Jiao WB, Patel V, et al.: Chromosome-level   assembly of Arabidopsis thaliana Ler reveals the extent of translocation and   inversion polymorphisms. Proc Natl Acad Sci 2016, 113:E4052–E4060.

6. Zhang J, Chen LL, Sun S,   Kudrna D, Copetti D, Li W, Mu T, Jiao WB, Xing F, Lee S, et al.:   Building two indica rice reference genomes with PacBio long-read and Illumina   paired-end sequencing data. Sci Data 2016, 3:160076.

7. Zhang J, Chen LL, Xing F,   Kudrna DA, Yao W, Copetti D, Mu T, Li W, Song JM, Xie W, Lee S, Talag J, Shao   L, An Y, Zhang CL, Ouyang Y, Sun S, Jiao WB, et al.: Extensive sequence divergence between the   reference genomes of two elite indica rice varieties Zhenshan 97 and Minghui   63. Proc Natl Acad Sci 2016, 113:E5163–E5171.

8. Gutjahr C, Gobbato E, Choi J,   Riemann M, Johnston MG, Summers W, Carbonnel S, Mansfield C, Yang SY, Nadal   M, Acosta I, Takano M, Jiao WB, et al.: Rice perception of symbiotic   arbuscular mycorrhizal fungi requires the karrikin receptor complex. Science   2015, 350:1521–1524.

9. Xu Q, Chen LL, Ruan X, Chen   D, Zhu A, Chen C, Bertrand D, Jiao WB, Hao BH, Lyon MP, et al.: The   draft genome of sweet orange (Citrus sinensis). Nat Genet 2013,   45:59–66.


备注

办公室 逸夫楼C508