杨庆勇

姓名

杨庆勇

性别

职称

副教授

学位

博士

电话

18986123521

邮箱

yqy@mail.hzau.edu.cn

工作单位

华中农业大学信息学院

研究方向

生物信息学;基因组学;系统遗传学

教育经历

2007.9 - 2012.6,华中农业大学,作物生物技术,博士。

2003.9 - 2007.6,华中农业大学,生物技术(双学位),学士。

2003.9 - 2007.6,华中农业大学,农村区域发展,学士。

主要职历

2016.12 - 至今,华中农业大学,信息学院,副教授,硕士生/博士生导师

2018-02至2018-08,新加坡国立大学,计算机学院,访问学者,导师: Sung Wing Kin, Ken,教授

2015.3 – 2016.12,华中农业大学,信息学院,副教授,硕士生导师

2012.7 - 2015.3,华中农业大学,生命科学技术学院,博士后

科研成果


主持或参加科研项目及人才计划项目情况

1、国家自然科学基金面上项目,32070559,油菜含油量主效位点BnPMT6的生物学功能与作用机理研究,2021/01-2024/12,直接经费58万元,主持。

2、国家重点研发计划(政府间国际科技创新合作重点专项),利用基因组学途径提高油菜含油量的合作研究,2017YFE0104800,2018/01-2020/12,363万元,在研,主持子课题。

3、国家重点基础研究发展计划(973计划),2015CB250100,油菜高产油量形成的分子生物学机制--高含油量油菜种胚油脂优势积累的代谢特点和分子基础(子课题4),2015/01-2019/12,208万元,在研,参加。

4、中国博士后科学基金会特别资助项目,2014T70710,结合连锁和关联分析解析油菜高油酸性状的遗传基础,2014/06-2015/06,15万元,在研,主持。

5、国家自然科学基金青年科学基金项目,31301005,基于SNP芯片和重测序技术鉴定油菜中新的高油酸位点及其候选基因,项目编号: 2014/01-2016/12,25万元,在研,主持。

6、国家自然科学基金青年科学基金项目,31301091,基于三维结构信息预测蛋白质相互作用及其位点的计算研究,2014/01-2016/12,22万元,在研,参加。

7、国家自然科学基金面上项目,31371659,油菜粒重基因的图位克隆和功能分析,2014/01-2017/12,72万元,在研,参加。


代表性论文(*通讯作者,#并列第一作者)

1. Song Jia-Ming#, Guan Zhilin#, Hu Jianlin#, Guo Chaocheng, Yang Zhiquan, Wang Shuo, Liu Dongxu, Wang Bo, Lu Shaoping, Zhou Run, Xie Wen-Zhao, Cheng Yuanfang, Zhang Yuting, Liu Kede*, Yang Qing-Yong*, Chen Ling-Ling*, Guo Liang*. Eight high-quality genomes reveal pan-genome architecture and ecotype differentiation of Brassica napus. Nature Plants, 2020, 6(1): 34~45.(共同通讯作者,1区,5-year IF= 14.576,ESI高被引)
2. Gao, Yingjie#, Yang, Zhiquan#, Yang, Wenqian#, Yang, Yanbo, Gong, Jing*, Yang, Qing-Yong*, & Niu, Xiaohui*. Plant-ImputeDB: an integrated multiple plant reference panel database for genotype imputation. Nucleic Acids Res. 2020, doi:10.1093/nar/gkaa953(共同通讯作者,1区,5-year IF = 11.797)
3. Song Jia-Ming#, Liu Dongxu #, Xie Wen-Zhao, Yang Zhiquan, Guo Liang, Liu Kede, Yang Qing-Yong*, Chen Ling-Ling*. BnPIR: Brassica napus Pan-genome Information Resource for 1,689 accessions. Plant Biotechnol J. 2020, doi:10.1111/pbi.13491(共同通讯作者,1区,5-year IF = 7.658)
4. Tang Shan, Liu DongXu, Lu Shaoping, Yu Liangqian, Li Yuqing, Lin Shengli, Li Long, Du Zhuolin, Liu Xiao, Xiao Li, Ma Wei, Yang Qing-Yong*, Guo Liang* (2020). Development and screening of EMS mutants with altered seed oil content or fatty acid composition in Brassica napus. Plant J. 2020, doi:10.1111/tpj.15003(共同通讯作者,1区,5-year IF = 6.629)

5. Wang, Maojun#; Wang, Pengcheng; Lin, Min*; Ye, Zhengxiu; Li, Guoliang*; Tu, Lili; Shen, Chao; Li, Jianying; Yang, Qingyong*; Zhang, Xianlong*. Evolutionary dynamics of 3D genome architecture following polyploidization in cotton. Nature Plants, 2018, 4(2): 90~97. (共同通讯作者,1区,2018 IF = 13.297)

6. Tao, Jingfen#; Zhou, Jinzhi; Xie, Ting; Wang, Xiaotao; Yang, Qingyong*; Zhang, Hongyu. Influence of chromatin 3D organization on structural variations of the Arabidopsis thaliana genome. Molecular Plant, 2017, 10(2): 340~344.(通讯作者;1区, 2018IF = 10.812)

7. Xie, Ting#; Yang, Qingyong#; Wang, Xiaotao; McLysaght, Aoife*; Zhang, Hongyu*. Spatial colocalization of human ohnolog pairs acts to maintain dosage- balance. Molecular Biology and Evolution. 2016, 33(9): 2368~2375. (并列第一作者;1区,2018 IF = 14.797)

8. Xie, Ting#; Zheng, Juefei#; Liu, Sheng; Peng, Cheng; Zhou, Yongming; Yang, Qingyong*; Zhang, Hongyu. De novo plant genome assembly based on chromatin interactions: A case study of Arabidopsis thaliana. Molecular Plant. 2015, 8(3): 489~492. (通讯作者;1区,2018 IF = 10.812)

9.Yang Q, Fan C, Guo Z, Qin J, Wu J, Li Q, Fu T, Zhou Y *. Identification ofFAD2andFAD3genes inBrassica napusgenome and development of allele-specific markers for high oleic and low linolenic acid contents. Theor Appl Genet. 2012 Aug; 125(4):715-29. doi: 10.1007/s00122-012-1863-1. Epub 2012 Apr 26.

10. Cai G#,Yang Q#, Yi B, Fan C, Edwards D, Batley J, Zhou Y *. A complex recombination pattern in the genome of allotetraploidBrassica napusas revealed by a high-density genetic map. PLoS One. 2014 Oct 30; 9(10):e109910. doi: 10.1371/journal.pone.0109910.

11. Liu H#,Yang Q#, Fan C*, Li Y, Wang X, Zhou Y *. Transcriptomic basis of functional difference and coordination between seeds and the silique wall ofBrassica napusduring the seed-filling stage. Plant Sci. 2015 Apr; 233:186-99.doi: 10.1016/j.plantsci.2015.01.015.

12. Cai G#,Yang Q#, Yi B, Fan C, Zhang C, Edwards D, Batley J, Zhou Y *. A novel bi-filtering method for processing of SNP array data improves the quality of genetic map and accuracy of QTL mapping in polyploidBrassica napus. BMC Genomic. 2015; 16(1):409.

13. Xie T#, Fu L#,Yang Q#, Xiong H#, Ma B*, Zhang H *, Xu H. Spatial features forEscherichia coligenome organization. BMC Genomic. 2015 Feb 5; 16(1):37.

14. Wang M, Tu L, Lin M,, Lin Z, Wang P,Yang Q, Ye Z, Shen C, Li J, Zhang L, Zhou X, Nie X, Li Z, Guo K, Ma Y, Huang C, Jin S, Zhu L, Yang X, Min L, Yuan D, Zhang Q, Lindsey K *, Zhang X *, Asymmetric subgenome selection and cis-regulatory divergence during cotton domestication. Nat Genet 2017; 49(4), 579–587, doi:10.1038/ng.3807

15. Cai G,Yang Q, Chen H, Yang Q, Zhang C, Fan C, Zhou Y *. Genetic dissection of plant architecture and yield-related traits in Brassica napus. Sci Rep. 2016 Feb; 16;6:21625. doi: 10.1038/srep21625.

16. Fan C, Wu Y,Yang Q, Yang Y, Meng Q, Zhang K, Li J, Wang J, Zhou Y *. A Novel Single-Nucleotide Mutation in a CLAVATA3 Gene Homolog Controls a Multilocular Silique Trait in Brassica rapa L. Mol Plant. 2014 Dec 7(12):1788-92. doi: 10.1093/mp/ssu090.

17. Hua Y, Zhou T, Ding G,Yang Q, Shi L, Xu F *. Physiological, genomic and transcriptional diversity in responses to boron deficiency in rapeseed genotypes.J Exp Bot. 2016 Oct;67(19):5769-5784.

18. Li Q, Yin M, Li Y, Fan C,Yang Q, Wu J, Zhang C, Wang H, Zhou Y *. Expression of Brassica napus TTG2, a regulator of trichome development, increases plant sensitivity to salt stress by suppressing the expression of auxin biosynthesis genes. J Exp Bot. 2015 Sep;66(19):5821-36.

19. 陶婧芬#, 谢婷#, 郑觉非, 杨庆勇 *, 张红雨 *. 基于染色质交互数据的基因组组装方法 生物技术通报, 2015, 31(11): 43-50. (约稿综述)


发明专利授权情况

(1) 张红雨,杨庆勇,全源,罗志辉,朱丽达,多靶标药物和/或药物组合的筛选方法,中国, CN201510288863.8,授权时间:2017-09-15(已转化

(2) 周永明;刘晟;范楚川;杨庆勇;一种与甘蓝型油菜含油量QTL紧密连锁的分子标记,中国,CN201610013828,华中农业大学,授权时间:2018-04-18

(3) 张红雨; 全源; 王晖; 朱丽达; 许璇; 杨庆勇; 黄清,一种基于热扩散网络的药物发现方法及其应用,中国,CN201710917312.2,华中农业大学,授权时间:2019-09-06

(4) 张红雨,朱丽达,罗志辉,全源,朱强,杨庆勇,一种基于机器学习的药物活性预测方法,中国, CN201610067573.5,授权时间:2017-04-12(已转化


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